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Amount in moles equivalent The mole is a unit of measurement used in chemistry to express amounts of a chemical substance solution and mole is widely used in chemistry, instead of units of mass or volume, as a convenient way to express the amounts of reactants and products of chemical reactions. For example, the chemical equation 2 H2 + O2 rarr; 2 H2O implies that 2 mol of dihydrogen and 1 mol of dioxygen react to form 2 mol of water. The mole may also be used to express the number of atoms, ions, or other elementary entities in some sample.