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Humans have been genetically modifying plants from the beginning of agriculture.

The "old" methods (still used today) were of combining two plants with favorable traits together to form a better strain.
Imagine growing apples and having two variants. One that has large and delicious apples, but which grow at a normal speed and a variant with quick growing but normal apples. If i were to combine these two to make a new variant that has large apples and grows quickly, that would be great.
This crossbreeding is the oldest kind of genetically modifying. As this is a (nearly) completely natural process no harm is done in my opinion

Gene-modded food (especially transgenics) is a bit more touchy. I believe that these are also ethical, but should not be haphazardly released into ecosystems to prevent disturbances/damage. A lot of transgenics are very useful, like the "Golden Rice" which makes vitamin A (normal rice does not do this) or crops that are more water resistant.